Despite its intimate nature, this theater has become a hub for Midwestern musical comedy. Originally located in the Radisson Plymouth hotel, the playhouse now resides in the Plymouth Best Western. The theater has made a name for itself through its host of hilarious off-Broadway musicals, including but not limited to the notoriously sidesplitting Church Basement Ladies—a Plymouth Playhouse original that has travelled far and wide since its conception in 2005. With 211 famously roomy seats, the playhouse packs it in.